
Does Turkey Really Make You Sleepy? The Truth About Tryptophan
Every year after Thanksgiving dinner, someone jokes that the turkey put them straight to sleep. The idea sounds believable—turkey contains tryptophan, an amino acid involved in producing calming brain chemicals. But is turkey actually powerful enough to knock you out after a holiday meal?
The short answer: not really. The long answer: your body, your meal, and your habits play a much bigger role than tryptophan alone.
What Is Tryptophan?
Tryptophan is an essential amino acid your body uses to make:
- Serotonin, a neurotransmitter that supports mood and relaxation
- Melatonin, the hormone that regulates your sleep–wake cycle
You get tryptophan through food—primarily protein sources like poultry, eggs, dairy, and nuts. This is where turkey gets its reputation.

Does Turkey Actually Have a Lot of Tryptophan?
Turkey does contain tryptophan, but here’s the twist: gram for gram, turkey is not higher in tryptophan than chicken or beef. Many everyday foods contain the same amount—or more.

To feel noticeably sedated from tryptophan alone, you would need:
- The right type of carbohydrates
- Eaten on an empty stomach
- At the right ratio to protein
A typical Thanksgiving plate doesn’t fit that formula.
So Why Do You Get Sleepy After Thanksgiving?
It’s not the turkey. It’s everything else.

1. A Massive Carbohydrate Load
Mashed potatoes, stuffing, rolls, pie—this carb overload spikes insulin, which can lead to a rebound drop in blood sugar that triggers fatigue.
2. “Rest and Digest” Mode
After a large meal, your body redirects blood flow to your digestive system. This activates the parasympathetic nervous system and makes you feel sleepy and heavy.
3. Alcohol
Wine, beer, and cocktails are central nervous system depressants and can amplify drowsiness.
4. Circadian Rhythm & Stress
Thanksgiving meals often happen mid-afternoon, right around your natural energy dip. Add travel, hosting, and family stress, and you have a perfect storm for a post-meal crash.
None of these have anything to do with turkey’s tryptophan levels.
Is Tryptophan Actually Good for Sleep?
Yes—but not in the way people think. Tryptophan can support:
- Sleep quality
- Mood
- Stress resilience
The best food sources include:
- Turkey & chicken
- Eggs & dairy
- Nuts & seeds
- Oats & legumes
It’s the pattern of your eating habits, not a single holiday plate, that matters.

Bottom Line
Turkey isn’t what makes you pass out after Thanksgiving dinner. The real crash comes from:
- Heavy carb intake and large portions
- Alcohol
- Your natural circadian rhythm
- Stress and being off your usual routine
Turkey just gets blamed because it sounds scientific. Still—enjoy it. Your post-meal nap is well-earned.
Want to talk about nutrition, sleep, or metabolic health?
As a direct primary care practice, we take the time to go beyond quick fixes and help you understand how your lifestyle affects your energy, weight, and sleep.
Schedule a visit with Dr. Shor